444 22 41
E-Sistem Login|EN / TR
Sistem PatentSistem Patent
Menu
Trademark
Trademark RegistrationLogo RegistrationSlogan RegistrationTrademark SearchRegistration ProcessTrademark ClassesFile TrackingInternational RegistrationMadrid ProtocolTrademark RenewalPublication OppositionTrademark MonitoringTrademark AssignmentTrademark LicensingCease-and-Desist Notice
Patent
Patent RegistrationPatent ApplicationPatent SearchUtility ModelPatent MonitoringInternational RegistrationPCT ApplicationEuropean Patent ApplicationInternational Patent SearchPatent ValuationRegister ChangesPatent OppositionPatent AssignmentPatent Licensing
Design
Design RegistrationDesign SearchIndustrial DesignIndustrial Design PatentDesign MonitoringRegistration IncentivesEU Design RegistrationInternational RegistrationRegistration OppositionRegistration RenewalCease-and-Desist NoticeRegistration AssignmentLegal Services
Copyright
Software CopyrightFine Art CopyrightMusic Work RegistrationMusic Copyright ApplicationSong Lyrics RegistrationComposer RegistrationGeographical IndicationDatabase RegistrationPlant Variety RegistrationIntellectual PropertyGetting a Barcode NumberProduct BarcodeDomain Names
Corporate
About UsReferencesBlogFAQContactIstanbul OfficeAnkara OfficeIzmir OfficeGermany OfficeUSA OfficeFile TrackingOnline PaymentBook Appointment
ContactSign UpSign In
European Patent (TR Translation)

Bisiklik Nitrojen İçeren Aromatik Heterosiklik Amid Bileşik.

Invention Abstract

Mevcut buluş; mükemmel Kompleks I inhibitör etkisine ve AMPK aktivasyon etkisine sahip olan ve meme kanseri için bir terapötik ilaç olarak kullanışlı olan formül (I)'e ait bisiklik nitrojen içeren aromatik heterosiklik amid bileşiği eya bunun bir tuzu ile ilgilidir. Bu bileşik, MCT4 eksprese etmeyen bir insan PIK3CA mutasyon pozitif meme kanseri hücre hattı üzerinde ve MCT4 eksprese etmeyen ve PIK3CA mutasyonuna sahip olmayan insan meme kanseri hücre hattı üzerinde hücre büyüme inhibe edici etkiye sahiptir ve insan PIK3CA mutasyon-pozitif meme kanseri hücre hattı MDA-MB-453 hücre tümörü taşıyan farelerde antitümör etkisi sergilemektedir.

IPC Classes
C07D 215/48A61K 31/497C07D 471/04C07D 401/04A61P 35/00A61K 31/496C07D 401/14C07D 235/30A61P 15/14C07D 413/14C07D 401/12C07D 471/14C07D 405/14
Parties
Inventor
Keı Ohnukı C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Hıdenorı Azamı C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Yukı Sawada C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Takashı Shın C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Takeyukı Nagashıma C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Shıgetoshı Kıkuchı C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Tomoyukı Saıto C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Hısao Hamaguchı C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya Kazuyukı Kuramoto C/O Astellas Pharma Inc. 5-1 Nihonbashi-Honcho 2- Chome Chuo-Ku Tokyo 103-8411 Japonya
Rights Holder
Astellas Pharma Inc. 5-1, Nihonbashi-Honcho 2-Chome Chuo-Ku Tokyo 103-8411 Japonya
Attorney
Uğur Gürşad Yalçıner (Yalçıner Patent Ve Dan. Ltd. Şti.) Tunus Caddesi No:85/8 - Çankayaankara

This record is compiled from official TPMK patent bulletins and is provided for information. The abstract text is as published, in Turkish. The current legal status (opposition, assignment, invalidation) requires a full register review. Ask our experts for a comprehensive patent search.