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European Patent (TR Translation)

Cd40'ı Antagonize Eden Antikor Polipeptitleri.

Invention Abstract

İnsan CD40?ın yeni bir epitopunu spesifik olarak bağlayan antikor polipeptitleri sağlanır. Antikor polipeptitler, CD40 agonist aktivitesi sergilemez. Antikor polipeptitler, otoimmün hastalıklar gibi CD40 aktivasyonunu içeren hastalıkların tedavisinde faydalıdır. Antikor polipeptitler, tek bir VL veya VH domeni içeren domen antikorları (dAb?ler) olabilir. Antikor polipeptitlerinin yarılanma ömrü, antikor polipeptitlerinin ayrıca insan serum albumini (HSA) bağlayabilen çift spesifik reaktifler olmak üzere modifiye edilmesi ile arttırılabilir.

IPC Classes
C07K 16/28A61K 39/395
Parties
Inventor
Anısh Surı Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. Steven Sherıff Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. Suzanne Suchard Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. Aaron Yamnıuk Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. Phılıp Drew 315 Cambridge Science Park Cambridge Cambridgeshire Cb4 0wg İngiltere James Tamura Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. James Bryson Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D. Steven Grant Domantis Limited 315 Cambridge Science Park Cambridge Cambridgeshire Cb4 0wg İngiltere Stanley Krystek Bristol-Myers Squibb Company Route 206 & Province Line Road Princeton, Nj 08543 A.B.D.
Rights Holder
Brıstol-Myers Squıbb Company Route 206 And Province Line Road Princeton, Nj 08543 A.B.D. Domantıs Lımıted 980 Great West Road Brentford, Middlesex Tw8 9gs İngiltere
Attorney
Tolga Çaylak (Dış Patent Marka Tescil Ve Danışmanlık Hiz. Ltd. Şti.) İçerenköy Değirmenyolu Cad. No:12/7 K:5 Ataşehir/İstanbul

This record is compiled from official TPMK patent bulletins and is provided for information. The abstract text is as published, in Turkish. The current legal status (opposition, assignment, invalidation) requires a full register review. Ask our experts for a comprehensive patent search.