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European Patent (TR Translation)

T Hücresi Reseptörleri

Invention Abstract

Mevcut buluş, MAGE-A4 proteininden türetilen HLA-A*0201 kısıtlı peptit GVYDGREHTV'yi (SEKANS KİMLİK No: 1) bağlayan T hücresi reseptörleri (TCR'ler) ile ilgilidir. Buluşun TCR'leri, bu MAGE epitopu için mükemmel özgüllük profilleri sergilemektedir. Ayrıca TCR'leri kodlayan nükleik asitler, TCR'leri sunmak üzere tasarlanmış hücreler, TCR'leri kodlayan ekspresyon vektörlerini barındıran hücreler ve buluşun TCR'leri, nükleik asitleri veya hücrelerini içeren farmasötik bileşimler de sağlanmaktadır.

IPC Classes
C07K14/725C07K14/47
Parties
Inventor
Nicholas Trıbble Eleanor Bagg William Lawrance
Rights Holder
Adaptımmune Lımıted 60 Jubılee Avenue Mılton Park Abıngdon, Oxfordshıre Ox14 4rx Birleşik Krallık
Attorney
Uğur Gürşad Yalçıner (Yalçıner Patent Ve Dan. Ltd. Şti.)

This record is compiled from official TPMK patent bulletins and is provided for information. The abstract text is as published, in Turkish. The current legal status (opposition, assignment, invalidation) requires a full register review. Ask our experts for a comprehensive patent search.