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European Patent (TR Translation)

T Hücresi Reseptörleri

Invention Abstract

Mevcut buluş, germ hattı kanser antijeni PRAME'den türetilen HLA-A*02 kısıtlı peptit SLLQHLIGL (SEQ ID NO: 1)'e bağlanan T hücresi reseptörleri (TCR'ler) ile ilgilidir. Söz konusu TCR'ler, doğal bir PRAME TCR'ye göre alfa ve/veya beta değişken alanları içinde doğal olmayan mutasyonlar içerebilir. Buluşa ait TCR'ler, kötü huylu hastalığın tedavisine yönelik yeni immünoterapötik reaktifler olarak kullanım için özellikle uygundur.

IPC Classes
C07K14/725C07K14/47A61K39/00
Parties
Inventor
William Philip Addıs Joy Nicole Bedke Lucie Bouard Pádraic Ronan O'dwyer Nathaniel Lıddy Tara Mahon Stephen Harper
Rights Holder
Immunocore Lımıted 92 Park Drıve Mılton Park Abıngdon, Oxfordshıre Ox14 4ry Birleşik Krallık
Attorney
Tolga Çaylak (Dış Patent Marka Tescil Ve Danışmanlık Hiz. Ltd. Şti.)

This record is compiled from official TPMK patent bulletins and is provided for information. The abstract text is as published, in Turkish. The current legal status (opposition, assignment, invalidation) requires a full register review. Ask our experts for a comprehensive patent search.